Sunday, 8 January 2012

Japanese researchers discover link between cholesterol and Alzheimer's

A recent Japanese study showed a link between high cholesterol and Alzheimer's disease. The study, published recently in the medical journal of the American Academy of Neurology that people who suffer from high levels of cholesterol face a higher risk of Alzheimer's cases.

Said study author Kinsok Sasaki of the University of Kyushu, Japan "We discovered that increased levels of cholesterol are related to the appearance of large patches of the brain associated with Alzheimer's disease."

In this study, the researchers examined the case of 2587 people aged between 40 to 79 years who do not show symptoms of Alzheimer's disease. They then examined the bodies of 147 people who died after a long period of observation (10 to 15 years). Among them were 50 people diagnosed with dementia before death injury. The search for the existence of snuff spots in the brain and other signs of Alzheimer's disease.

It was found that people who suffer from high cholesterol noon to have the largest cerebral spots compared to persons who have normal levels of cholesterol. About 86% of people who suffer from high cholesterol in their blood stains the brain, compared with 62% of those who have low levels of cholesterol.

In addition to increasing the proportion of cholesterol as a risk factor for Alzheimer's disease researcher found that insulin resistance may represent a risk factor for the last patches of cortex that are associated with Alzheimer's disease.

This study shows clearly the potential impact of increased cholesterol patches on the backs of the brain directly or indirectly, except that the failure of drug treatment for high cholesterol in the treatment of Alzheimer's means there is no link between cholesterol reduction and prevention of Alzheimer's disease. "

Experts: "Chrome" browser will become the number one in the world of the Internet

Managed company "Google" about a month ago in the upgrading of the web browser "Chrome", which is owned to the second place among Internet browsers, surpassing the "Firefox", and is widely expected that the "Chrome" may succeed in the near future to get rid of the "Internet Explorer" on top of the list, to become the number one browser for the Internet.

According to the company "Stikaontr" specialized in the analysis of network data, accounted for "Chrome" with 27% share of the use of the Internet in December / January, compared to "Internet Explorer" which accounted for 37% of the market, a decline in the rate of 2% over the month the previous year, while Firefox has a solution in the third place by 25%.

And analyst David Mitchell Smith that "Chrome" because it derives its strength from a strong product, and commented: "People use it because it is a fast browser, and Google has spent a lot to promote it, which increased the awareness of users of its characteristics."

Smith said today that the user has a lot of options on Internet browsers, For several years the "Internet Explorer" is the highest share in the market, being part of a free Windows.

The success of the "Chrome" in Google's efforts to expand their business outside the famous search engine, and mobile operating systems "Android" and social networking sites "Google Plus."

Researchers discover genetic changes cause cancer of the thyroid gland

Enable U.S. researchers identify 3 of the genetic changes cause cancer, thyroid, and one of these changes shall be known as gene PTEN gene, which increases the risk of children with the disease.

She said Director of the Institute of gene therapy at Cleveland Clinic, Dr. Haraz Inge said: "We have managed the research team to study the genetic changes behind the thyroid disease has resulted in a reach of important details to help diagnose and treat disease, and hope that this study in the early detection of disease and access to the best treatment possible." .

To access the relationship between cancer risk and genetic changes, the researchers examined the follow-up nearly 3 thousand patients each were diagnosed with another disease known Cowden syndrome, a rare disease caused by defective tissue resulting in multiple tumors.

This study focused on mutations in 3 genes, known as PTEN and SDH and KLLN and because the entire work is focused on methods of remote cell therapies should be designed to reduce the risk of cancer targeting each gene separately.

The researchers discovered that mutations gene PTEN are associated with increased risk of thyroid cancer, in addition to signals for mutations other in the genes PTEN and SDH and KLLN may be included in the emergence of the problem as well, but the gene, the first is responsible for injury to children under the age of 18 years of thyroid cancer, and good luck is a test gene PTEN key element in the world of analysis of genes, as confirmed by the study.

The thyroid cancer recorded the largest increase among all other types of cancer that affects both men and women alike, and the PTEN gene is the inhibitor of the tumors and when it is in healthy condition helps in the growth and cell division.

However, inherited mutations of this gene and hinder the function of the gene and Tdjah help in the growth of tumors. This irregularity in the function of this gene is found in about 80% of patients with Cowden syndrome who are at high risk of breast cancer and thyroid.